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Pharmaceuticals

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Category: Pharmaceuticals

What to Look For When Buying Nutritional Supplements

What to Look For When Buying Nutritional Supplements

pillsThere are quite literally hundreds of different brands of nutritional supplements (also called dietary supplements) on the market today, and it’s difficult for the average consumer to tell the difference between one and another. Each manufacturer claims that its products are supportive of your health, but how can you really determine if a nutritional supplement is safe and effective? Then there’s the price tag. Brands vary considerably in cost—one multivitamin may cost 20 cents per day, whereas another can cost a whopping $7.50! How can you decide whether it’s worth it? Our goal is to provide you with some practical advice—basic facts combined with a few do’s and don’ts—that you can use to be a more educated consumer if you decide to buy nutritional supplements.

Just because a nutritional supplement is “natural” does NOT necessarily mean it is safe. There are plenty of products that can be dangerous if you suffer from certain health conditions, use them along with certain other foods, medicines or supplements, or take them incorrectly. Even if you avoid interactions and take a supplement correctly, it is still possible for your body to have a negative reaction to a supplement. If this happens, stop taking the supplement immediately and see your doctor.

The FDA regulates dietary supplements very lightly. A supplement manufacturer does not need FDA approval to put its products on the market, but the FDA is responsible for monitoring the products’ safety, removing them only if they have caused problems. However, the FDA does require that manufacturers follow “good manufacturing practices” for processing and that they meet quality standards. This includes ensuring that the supplement contains the stated amount of ingredients and that it is free from contamination from things such as pesticides and heavy metals.

One thing to look for in a nutritional supplement is the “USP Verified” seal of approval. This is given to products that meet the stringent requirements for quality, purity and potency as established by the non-profit group U.S. Pharmacopeia.

The form in which you take your dietary supplements may also make a difference. Tablets tend to contain more fillers and binders than capsules because the powder they are made from must stick together in a regular mass. They may also be coated to keep it from falling apart and to make swallowing easier. They may also have added coloring and flavoring to make them more palatable. All else equal, it usually makes sense to avoid these. Capsules or gel caps are more likely to be free from excess fillers and binders. But if you are vegetarian or vegan, be sure to read the label to ensure the capsules are not derived from animal sources (cellulose is the most common vegan-friendly form of capsule).

Always read the product’s label thoroughly to see exactly what each supplement contains. While buying the most expensive supplement obviously won’t guarantee its quality or effectiveness, it is often true that you get what you pay for. Cheap supplements are frequently made from inferior ingredients or those that cost less to manufacture, and are often less readily absorbed by the body. Who wants to pay for supplements only to have them flushed down the toilet? A high-quality supplement will be more bioavailable, which is what you’re taking it for in the first place!

As with most other products, it usually pays to do a little homework before choosing a manufacturer and buying a supplement. Above all, you’ll want a manufacturer who has a good reputation and stands behind its products. Good companies will stress their excellent quality control and will be happy to provide you with independent evaluations of their products. Many chiropractors have specialized training and experience related to nutrition, and can help you decide which dietary supplements might be right for you.

Head-to-Head: Chiropractic Adjustments or NSAIDs for Acute Lower Back Pain?

Head-to-Head: Chiropractic Adjustments or NSAIDs for Acute Lower Back Pain?

???????????????????????Lower back pain (LBP) is so widespread that it was listed in the 2010 Global Burden of Disease report as being the single leading cause of disability worldwide. Over half of all working Americans have lower back pain symptoms each year, resulting in lost work time and enormous expense – Americans spend over $50 billion each year to treat their back pain.

So it’s not surprising that a great deal of research is being conducted to determine the most effective methods for treating acute LBP. Much of this research has sought to compare the effectiveness of spinal manipulation (the sort of adjustments performed by Doctors of Chiropractic) with nonsteroidal anti-inflammatory drugs (NSAIDs). While these studies have generally not produced definitive findings one way or the other, they have served to highlight potential safety concerns related to NSAIDs. For example, investigators in one study found that diclofenac (an NSAID commonly used to treat LBP) increased the risk of gastrointestinal complications by 54% and posed other risks to the kidneys.

Given the added concern about NSAID side effects, researchers and clinicians have had a renewed interest in learning whether drug-free manual therapies—chiropractic care, in particular—can really be just as effective, but safer. According to a recent study published in the April 2013 edition of the journal Spine, the answer is YES! In fact, the research team that conducted the study found that chiropractic adjustments were both safer and FAR MORE EFFECTIVE.

In this study, investigators divided a total of 101 patients suffering from acute lower back pain into three groups. One group received chiropractic spinal manipulation plus a placebo (sham) version of the NSAID diclofenac (meaning that the only treatment actually being offered was chiropractic care). A second group received sham spinal manipulation and real diclofenac (meaning that the NSAID was the only treatment being employed). And a third group received the same sham spinal manipulation plus placebo diclofenac (meaning that no treatment was actually being offered – this was the “control group”). All treatments were “blinded,” meaning that the patients did not know whether they were receiving real or sham spinal manipulation or real or placebo diclofenac. Outcomes were measured based on a combination of patient self-reporting, physical examination, missed work time, and the amount of rescue medication (paracetamol tablets) participants required over a 12-week period.

Perhaps unsurprisingly, about half of the participants in the “control” group receiving no treatment dropped out of the study because of intolerable pain. Comparing the remaining no-intervention subjects and the two remaining intervention groups, researchers found that the group receiving chiropractic high-velocity low-amplitude (HVLA) manipulation fared significantly better than the group being treated with diclofenac and the control group.

Researchers reported a clear difference between the two intervention groups: “The groups receiving spinal manipulation showed a faster and more distinct reduction in the RMS [root mean square, a standardized test of flexibility and mobility]. Subjects also noted a faster and quantitatively more distinct reduction in their subjective estimation of pain after manipulation.” They also found that the group treated only with the NSAID diclofenac required more rescue medication (paracetamol) than the spinal manipulation group, taking 3 times as many tablets and for twice the number of days. No negative effects were reported from the spinal manipulation group, but several negative effects were reported from the diclofenac group.

So, overall, this study indicates a clear “win” for chiropractic in the treatment of acute lower back pain. Not only does HVLA spinal manipulation avoid the potential safety concerns of NSAID medications such as diclofenac, it has been found to be far more effective. Remember this the next time you experience lower back pain, and consider seeing your chiropractor first. This one simple decision may help you recover more quickly and more completely while also helping you avoid the negative side effects of NSAIDs.

 

Close Up On Adverse Drug Reactions

Close Up On Adverse Drug Reactions

???????????You can’t switch on a television these days without seeing a commercial for some new pharmaceutical that will cure whatever may ail you (or cure you from an illness you never knew you had). If you pay attention to it, you will notice that nearly half the ad time is taken up with a long list of possible side effects and adverse reactions that may accompany taking the drug. The possibilities often include everything from slight fatigue to death.

An estimated 4.5 million Americans visit their doctor or the ER each year due to adverse reactions to prescription drugs. These adverse side effects are also suffered by an additional 2 million people each year who are already in the hospital being supervised by medical professionals. The CDC estimates that 82% of Americans are taking at least one drug, and 29% are taking five or more drugs.

 
The US Food and Drug Administration (FDA) is in charge of approving pharmaceutical drugs for sale in the US. However, their methods for approval are based on the drug companies providing their own scientific studies on the safety of the drug. The FDA does no independent testing. The FDA will usually approve a drug if its benefits are believed to outweigh its dangers. Even assuming the drug companies’ studies have been well-conducted and show that a drug is relatively safe, no drug is completely free from side effects for everyone, even those drugs that are “natural.” A person’s age, weight, gender, overall health and genetic profile have a lot to do with how an individual will respond to a drug.

The most common side effects are gastrointestinal problems, as most drugs are processed via the digestive tract. These problems include nausea, vomiting, constipation and diarrhea. Other common side effects are drowsiness, fatigue and mild skin reactions. Although dizziness may not seem like a dangerous side effect, it can be particularly risky for seniors. According to the Centers for Disease Control and Prevention (CDC), falls among seniors are the leading cause of injury-related death. A quarter of all seniors who fall and break a hip will die within six months of receiving the injury.

Death is of course the most serious side effect of all. Allergic reactions that cause anaphylaxis can be deadly. Some drugs, such as those that treat type 2 diabetes (Actos and Avandia, for example) can cause a stroke or heart attack. Antidepressants can actually increase suicidal thoughts. Some drugs can cause pain and total or partial paralysis, such as the cholesterol-lowering drug Lipitor. Some drugs increase your risk of cancer. Ironically, the drug Tamoxifen, prescribed to treat breast cancer, actually increases the risk of uterine cancer. Memory loss, hallucinations, loss of taste and loss of sight are other common side effects of pharmaceuticals.

 
Although there is no doubt that some pharmaceuticals are far more useful than they are dangerous (antibiotics, for example), if you want to avoid the harmful side-effects that many drugs may produce, try to keep as healthy as possible. Eat right, get regular exercise and visit your chiropractor to keep your body in top condition.